Advanced Breast Cancer Treatment – search4answers.com

Advanced Breast Cancer Treatment

Ads related to
advanced breast cancer treatment

In most cases, the standard treatment for stage IV—advanced or metastatic breast cancer—involves systemic treatment. This treatment approach typically involves a combined use of chemotherapy, hormone therapy, and targeted therapy. Radiation therapy or surgery may also be recommended to control the symptoms.

Advanced breast cancer is a stage in which the tumour has spread to surrounding tissues outside the breast, such as the lymph nodes. In a majority of cases, when breast cancer metastasizes, it reaches into the lungs, liver, and bones. However, it can also spread to distant organs such as the brain.

Advanced Breast Cancer Treatment

For patients with advanced breast cancer, the primary method of treatment includes systemic medications through chemotherapy, targeted therapy, or hormone therapy. A combination of two or more of these methods can also be used. 

These therapies work by shrinking cancerous cells or impeding their growth rate. Some of them also relieve symptoms and prolong patients’ lives. That said, stage IV breast cancer is incurable; it can only be treated to enhance patients’ quality of life.

Systemic Therapies as Advanced Breast Cancer Treatment

Oncologists determine the most suitable drugs according to the patient’s breast cancer type in relation to its HER2 status and hormone receptor status.

ER-positive or PR-positive Cancers

Using hormone therapy that is comprised of either an aromatase inhibitor or tamoxifen is usually the first course of action for patients with hormone receptor-positive tumours. In some cases, this form of therapy may be used in conjunction with a targeted therapy medication such as abemaciclib or palbociclib.

ER-negative or PR-negative Cancers

Chemotherapy is the primary therapy for patients with hormone-receptor-negative cancers as hormone therapy does not work in fighting this particular type of cancer.

HER2-positive

The primary approach to treatment for HER2-positive cancers involves the use of the medication trastuzumab. In fact, trastuzumab is typically taken in conjunction with chemotherapy or hormone therapy drugs. It can also be taken with anti-HER2 medications.

HER2-negative

HER2-negative cancer patients prefer chemotherapy as the most viable option. In the case of ER-positive or PR-positive cancers, chemotherapy may be used in conjunction with hormone therapy. Following a course of chemotherapy, some patients are placed on a targeted agent known as a PARP inhibitor.

 

Featured Image: DepositPhotos/ IgorVetushko

RELATED BY

  • deep vein thrombosis medications

    Deep Vein Thrombosis Medications

    Deep vein thrombosis (DVT) is a medical condition that results from the formation of a blood clot in a deep vein in the body, typically affecting the legs. Patients...
  • hemophilia a treatment

    Hemophilia A Treatment

    Hemophilia is a rare, genetic blood condition in which the blood is unable to clot regularly due to a deficiency of clotting factors (proteins that enable clotting). People with...
  • NSCLC treatments

    NSCLC Treatments

    If you are diagnosed with non-small cell lung cancer (NSCLC), your medical team will go through every treatment option available to find those suited to your condition. It is paramount...
  • Pneumonia Shot

    Pneumonia Shot

    Pneumonia is a disease that most commonly occurs in young children under the age of two, as well as adults over the age of 65. People most susceptible to pneumonia...